Nanotechnology of Polymers and Biomaterials
group members
basic information
Nanotechnology of Polymers and Biomaterials group
The detailed information can be found at http://www2.chemia.uj.edu.pl/npb/
Nanotechnology of Polymers and Biomaterials Group (NPB) headed by prof. Szczepan Zapotoczny is involved in research of advanced polymeric and hybrid materials for nanotechnology, medicine and environmental protection. The research is carried out within six subunits under a direct supervision of the Associate or Assistant Professors being a group members. Their activity is concentrated on :
Molecular modelling of surfactant bilayers – Dr. Dorota Jamróz – leader
♦ structure and properties of surfactant bilayers
♦ interaction of small molecules of biological interest with surfactant or lipid bilayers
♦ parametrization of the force field for functional groups which are common constituents of ionic surfactants
Materials for controlled drug delivery – Dr. hab. Anna Karewicz – leader
♦ charged liposomes as carriers for biologically active molecules
♦ hydrogel micospheres of films from natural biocompatible polymers for sustained and/or controlled release of drugs
♦ stimuli-responsive polymers for controlled drug delivery and tissue engineering
Dispersed systems for biomedical applications – Dr. hab. Mariusz Kępczyński – leader
♦ porphyrins with covalently attached polymer chains as sensitizers in Photodynamic Theraphy (PDT)
♦ liposome-photoactive polymer hybride photosensitizers
♦ vesicles as drug vehicles
♦ nanocapsules and nanoparticles made from silica and silicone materials
Silicon nano- and microstructures – Dr. Joanna Lewandowska – leader
♦ silica nano- and microstructures
♦ surfactant stabilized vesicles and liposomes as carriers for biologically active molecules
♦ magnetic microspheres from silica precursors for biomedical applications
Polymeric and hybrid materials for biomedical and environmental applications – Prof. Krzysztof Szczubiałka – leader
♦ photochemical molecular imprinting of molecules of biomedical interest
♦ polymeric scaffolds for tissue culturing
♦ hybrid aluminosilicate-polymeric photosensitizers
♦ polymer-surfactant interactions
♦ stimuli-responsive ("smart") polymers for environmental and medical applications (purification of water from surfactants, removal of heparin from blood)
Nanoengineering of functional polymeric materials – Prof. Szczepan Zapotoczny – leader
♦ nanostructural polymeric materials for photochemical and biomedical applications
♦ Atomic Force Microscopy (AFM) – the primary technique for studies of soft matter - development of novel methods and their application in nanotechnology and nanomedicine
♦ energy/electron transfer processes in the confined environments
♦ photosensitized reactions in polymeric nanoreactors
♦ photochemistry and photophysics of selected compounds (e.g. Excited-State Proton Transfer)
The detailed information can be found at http://www.nfpm.chemia.uj.edu.pl/
Selected papers published in 2009-2011:
♦ K. Kamiński, M. Płonka, J. Ciejka, K. Szczubiałka, M. Nowakowska, B. Lorkowska, R. Korbut, R. Lach, "Cationic Derivatives of Dextran and Hydroxypropylcellulose as Novel Potential Heparin Antagonists", J. Med. Chem., Article in Press
♦ M. Golonka, M. Bulwan, M. Nowakowska, A. M. Testera, J. C. Rodríguez-Cabello, S. Zapotoczny, "Thermoresponsive multilayer films based on ionic elastin-like recombinamers", Soft Matter, 2011, 7, 9402-9409
♦ A. Karewicz, D. Bielska, B. Gzyl-Malcher, M. Kepczynski, R. Lach, M. Nowakowska, "Interaction of curcumin with lipid monolayers and liposomal bilayers", Colloid. Surface. B,
2011, 88, 231– 239
♦ M. Kepczynski, J. Lewandowska, K. Witkowska, S. Kedracka-Krok, V. Mistrikova, J. Bednar, P. Wydro, M. Nowakowska, "Bilayer structures in dioctadecyldimethylammonium bromide/oleic acid dispersions", Chem. Phys. Lipids, 2011, 164 (5), 359-367
♦ M. Staszewska, M. Dzieciuch, J. Lewandowska, M. Kepczynski, S. Zapotoczny, M. Oszajca, A. Łatkiewicz, M. Nowakowska, "Silica covered porphyrin microstructures obtained in sol-gel processes", J. Sol-Gel Sci. Techn., 2011, 59, 276-282
♦ M. Molenda, K. Furczon, A. Kochanowski, S. Zapotoczny, M. Szuwarzynski, B. Dudek, R. Dziembaj, "Application of gelcasting process in ceria membranes formation", Solid State Ionics, 2011, 188, 135-139
♦ A. Plewa, W. Niemiec, J. Filipowska, A. M. Osyczka, R. Lach, K. Szczubiałka, M. Nowakowska, "Photocrosslinkable Diazoresin/ Pectin Films - synthesis and application as cell culture supports", Eur. Polym. J., 2011, 47, 1503-1513
♦ M. Romek, B. Gajda, E. Krzysztofowicz,M. Kepczynski, Z. Smorag, "New technique to quantify the lipid composition of lipid droplets in porcine oocytes and pre–implantation embryos using Nile Red fluorescent probe", Theriogenology, 2011, 75 (1), 42–54
♦ X. Sui, S. Zapotoczny, E.M. Benetti, M. Memesa, M.A. Hempenius, G.J. Vansco, "Grafting mixed responsive brushes of poly(N–isopropylacrylamide) and poly(methacrylic acid) from gold by selective initiation", Polym. Chem., 2011, in press
♦ A. Karewicz, J. Łegowik, M. Nowakowska, "New bilayer-coated microbead system for controlled release of 5-aminosalicylic acid", Polym. Bull., 2011, 66, 433-443
♦ X. Sui, S. Zapotoczny, E.M. Benetti, P. Schön, G.J. Vancso, "Characterization and molecular engineering of surface-grafted polymer brushes across the length scales by atomic force microscopy", Journal of Materials Chemistry, 2010, 20 (24), 4981-4993
♦ M. Molenda, K. Furczon, A. Kochanowski, S. Zapotoczny, M. Szuwarzynski, B. Dudek, R. Dziembaj, "Application of gelcasting process in ceria membranes formation", Solid State Ionics, 2010, in press
♦ M. Kepczynski, M. Kumorek, M. Stepniewski, T. Róg, B. Kozik, D. Jamróz, J. Bednar, M. Nowakowska, "Behavior of 2,6-Bis(decyloxy)naphthalene inside lipid bilayer", Journal of Physycal Chemistry B, 2010, 114 (47), 15483-15494
♦ D. Drozd, K. Szczubiałka, M. Nowakowska, " Novel hybrid photosensitizers: Photoactive polymer-nanoclay", Journal of Photochemistry and Photobiology A: Chemistry, 2010, 215 (2-3), 223-228
♦ K. Wybranska, W. Niemiec, K. Szczubialka, M. Nowakowska, Y. Morishima, "Adenine Molecularly Imprinted Polymer-Coated Submicrometer Silica Gel Particles", Chemistry of Materials, 2010, 22 (18), 5392-5399
♦ W. Niemiec, S. Zapotoczny, K. Szczubialka, A. Laschewsky, M. Nowakowska, "Nanoheterogeneous Multilayer Films with Perfluorinated Domains Fabricated Using the Layer-by-Layer Method", Langmuir, 2010, 26(14), 11915-11920
♦ K. Gawel, K. Szczubialka, S. Zapotoczny, M. Nowakowska, "Zwitterionically modified hydroxypropylcellulose for biomedical applications", European Polymer Journal, 2010, 46(7), 1475-1479
♦ K. Kaminski, K. Szczubialka, K. Zazakowny, R. Lach, M. Nowakowska, "Chitosan derivatives as novel potential heparin reversal agents", Journal of Medicinal Chemistry, 2010, 53 (10), 4141-4147
♦ E.M. Benetti, X. Sui, S. Zapotoczny, G.J. Vansco, "Surface-grafted gel-brush/metal nanoparticle hybrids", Advanced Functional Materials, 2010, 20 (6), 939-944
♦ M. Elzbieciak, D. Wodka, S. Zapotoczny, P. Nowak, P. Warszynski, "Characteristics of model polyelectrolyte multilayer films containing laponite clay nanoparticles", Langmuir, 2010, 26 (1), 277-283
♦ A. Karewicz, K. Zasada, K. Szczubiałka, S. Zapotoczny, R. Lach, M. Nowakowska, "Smart alginate-hydroxypropylcellulose microbeads for controlled release of heparin", International Journal of Pharmaceutics, 2010, 385, 163–169
♦ J. Lewandowska, M. Kepczyński, J. Bednar, E. Rzad, V. Moravickova, B. Jachimska, M. Nowakowska, “Silicone-stabilized liposomes”, Colloid Polym. Sci., 2010, 2888:37–44
♦ Z. M. Prokopowicz, F. Arce, R. Biedroń, Ch.L.–L. Chiang, M. Cieszek, D. R. Katz, M. Nowakowska, S. Zapotoczny, J. Marcinkiewicz, B. M. Chain, “Hyperchlorous Acid: A Natural Adjuvant that Facilitates Antigen Processing, Cross–Priming, and the Induction of Adaptive Immunity", J. Immunol., 2010: 184, 824–835.
♦ M. Kepczyński, J. Bednar, D. KuĽmicz, P. Wydro, M. Noawkowska, “Spontaneous Formation of Densly Stacked Multilamellar Vesicles in Dioctdecyldimethylammonium Bromide/Oleosiloxane Mixtures", Langmuir, 2010, 26(3), 1551–1556.
♦ M. Bulwan, S. Zapotoczny, M. Nowakowska, "Robust one–component chitosan-based ultrathin films fabricated using layer–by–layer technique", Soft Matter, 2009, 5, 4726–4732.
♦ K. Nawalany, A. Rusin, M. Kępczyński, A. Mikhailov, G. Kramer–Marek, M. Snietura, J. Połtowicz, Z. Krawczyk, M. Nowakowska, "Comparison of photodynamic efficacy of tetraarylporphyrin pegylated or encapsulated in liposomes: In vitro studies", Journal of Photochemistry and Photobiology B: Biology, 2009, 97 (1), 8–17
♦ M. Elżbieciak, M. Kolasińska, S. Zapotoczny, R. Krastev, M. Nowakowska, P. Warszyński, "Nonlinear growth of multilayer films formed from weak polyelectrolytes", Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2009, 343 (1–3), 89–95
♦ J.S. De Klerk, A.N. Bader, S. Zapotoczny, M. Sterzel, M. Pilch, A. Danel, C. Gooijer, F. Ariese, "Excited–state double proton transfer in 1H–pyrazolo[3,4–b]quinoline dimers", Journal of Physical Chemistry A, 2009, 113 (18), 5273–5279
♦ E.M. Benetti, E. Reimhult, J. De Bruin, S. Zapotoczny, M. Textor, G.J. Vancso, "Poly(methacrylic acid) grafts grown from designer surfaces: The effect of initiator coverage on polymerization kinetics, morphology and properties", Macromolecules, 2009, 42 (5), 1640–1647
♦ M. Nowakowska, K. Nawalany, M. Kępczyński, Z. Krawczyk, "Novel nanostructural hybride materials for photodynamic theraphy", Macromolecular Symposia, 2009, 279 (1), 132–137
♦ M. Kępczyński, J. Bednar, J. Lewandowska, M. Staszewska, M. Nowakowska, "Hybrid silica–silicone nanocapsules obtained in catanionic vesicles. Cryo–TEM studies", Journal of Nanoscience and Nanotechnology, 2009, 9 (5), 3138–3143
♦ M. Elżbieciak, S. Zapotoczny, P. Nowak, R. Krastev, M. Nowakowska, P. Warszyński, "Influence of pH on the Structure of Multilayer Films Composed of Strong and Weak Polyelectrolytes", Langmuir, 2009, 25 (5), 3255–3259
More publications can be found at http://www2.chemia.uj.edu.pl/npb/links/publications.html
