| Applications of selected spectroscopic methods in studies of polymorphism in pharmaceutical solids | |
| Unit Code | ASC semester III |
| Credits | 10 |
| Laboratory | Phase Transitions Research Team |
| Location | Faculty of Chemistry, Jagiellonian University |
| Tutor name | Prof. Edward Mikuli |
| Phone | 48-12-6632256 |
| mikuli@chemia.uj.edu.pl druzbick@chemia.uj.edu.pl | |
COURSE DESCRIPTION: Phase transitions; characteristic of polymorphs; drug bioavailability; packing and conformational polymorphism; pseudopolymorphism; application of spectroscopic methods to study polymorphism; solid-state NMR, FT-IR, FT-RS, Neutron Scattering Techniques, interpretation of results; molecular crystals; molecular structure and intermolecular forces.
AIMS:
The most important aim is to acquaint student with spectroscopic methods of studying polymorphism with special focus on pharmaceutical solids.
INTENDED LEARNING OUTCOMES:
After completing this unit a student is expected to understand the most important concepts connected with phase transitions and polymorphs, with special focus on their role in the pharmaceutical industry. The student is expected to understand how the selected spectroscopic methods can be used in this field.
TEACHING AND LEARNING ACTIVITIES:
Tutorial: 60 h
Seminar: 10h
Student centered learning: 180 h
Total student effort: 250 h
ASSESSMENT:
Written report (67 %), oral presentation (33 %)
BIBLIOGRAPHY:
Adequate articles and research reports on the topic